3-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)propanoic acid
α-Amine-ω-propionic acid triethylene glycol
CAS: 784105-33-5
Molecular Formula: C9H19NO5
3-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)propanoic acid - Names and Identifiers
3-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)propanoic acid - Physico-chemical Properties
| Molecular Formula | C9H19NO5 |
| Molar Mass | 221.25 |
| Density | 1.137±0.06 g/cm3(Predicted) |
| Boling Point | 372.1±32.0 °C(Predicted) |
| pKa | 4.27±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| In vitro study | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
3-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)propanoic acid - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 4.52 ml | 22.599 ml | 45.198 ml |
| 5 mM | 0.904 ml | 4.52 ml | 9.04 ml |
| 10 mM | 0.452 ml | 2.26 ml | 4.52 ml |
| 5 mM | 0.09 ml | 0.452 ml | 0.904 ml |
Last Update：2024-01-02 23:10:35
3-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)propanoic acid - Reference Information
| biological activity | Amino-PEG3-C2-acid is a degradable (cleavable) 4-unit PEG ADC linker for the synthesis of antibody-coupled drugs (ADC). Amino-PEG3-C2-acid is a PEG-based PROTAC linker, which can be used for PROTAC synthesis. |
| target | Cleavable PEGs |
| in vitro study | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
Last Update：2024-04-09 20:52:54
3-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)propanoic acid - Introduction
Bioactive Amino-PEG3-C2-acid is a degradable (cleavable) 4-unit PEG ADC linker used in the synthesis of antibody-coupled drugs (ADC). Amino-PEG3-C2-acid is a PEG-based PROTAC linker, which can be used for PROTAC synthesis.
Target
Cleavable
PEGs
In vitro study
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Last Update：2024-04-09 21:04:16
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Product Name: 3-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]propanoic acid Visit Supplier Webpage Request for quotationCAS: 784105-33-5
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Product Name: 3-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)propanoic Acid Visit Supplier Webpage Request for quotationCAS: 784105-33-5
Tel: +86-18821248368
Email: Int06@meryer.com
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Product Name: α-Amine-ω-propionic acid triethylene glycol Visit Supplier Webpage Request for quotation
CAS: 784105-33-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 784105-33-5
Tel: 18301782025
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